一种新的淋巴细胞表面抗原，Ly-22.2，受4号染色体上的一个基因座和另一个不连锁的基因座控制。
A new lymphocyte cell surface antigen, Ly-22.2, controlled by a locus on chromosome 4 and a second unlinked locus.
作者信息
Meruelo D, Offer M, Flieger N
出版信息
J Immunol. 1983 Feb;130(2):946-50.
A serum raised by immunizing (B10.A(4R) X B10.HTT)F1 mice against A.AL lymphocytes detects a new antigenic determinant designated Ly-22.2. Ly-22.2 expression is under the control of two independently segregating genes, one of which maps to chromosome 4 adjacent to a locus affecting XenCSA expression. Ly-22.2 is present in varying amounts in all lymphoid organs, but appears to be expressed primarily on T lymphocytes. Ly-22.2 is not detectable in brain, kidney, lung, liver, or erythrocytes. Strain distribution studies show Ly-22.2 is present in all strains examined except B10-derived congenic strains. It is of interest that C57BL/6 and C57BL/10 mice differ in the expression of this antigen.
通过用A.AL淋巴细胞免疫（B10.A(4R)×B10.HTT）F1小鼠制备的血清检测到一种新的抗原决定簇，命名为Ly-22.2。Ly-22.2的表达受两个独立分离基因的控制，其中一个基因定位于4号染色体上，与一个影响XenCSA表达的位点相邻。Ly-22.2在所有淋巴器官中的含量各不相同，但似乎主要在T淋巴细胞上表达。在脑、肾、肺、肝或红细胞中未检测到Ly-22.2。品系分布研究表明，除了B10衍生的同源品系外，在所有检测的品系中都存在Ly-22.2。有趣的是，C57BL/6和C57BL/10小鼠在这种抗原的表达上存在差异。
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