Berkowitz R S, Ehrmann R L, Knapp R C
Obstet Gynecol. 1978 Jan;51(1 Suppl):34s-37s.
The present case reports the concurrence of endometriosis of the vaginal cuff with endometrial stromal sarcoma in association with high-dose estrogen. This case raises the question of whether chronic high-dose estrogen might be associated with malignant transformation of endometrial stroma. Although there is no definitive evidence of a causal relation between estrogen and endometrial stromal sarcoma, the possibility should be explored further. Therapy of this neoplasm is discussed and salient clinical and pathologic features are reviewed.
本病例报告了阴道断端子宫内膜异位症与子宫内膜间质肉瘤合并高剂量雌激素的情况。该病例提出了慢性高剂量雌激素是否可能与子宫内膜间质恶性转化相关的问题。尽管尚无确凿证据表明雌激素与子宫内膜间质肉瘤之间存在因果关系，但仍应进一步探讨这种可能性。本文讨论了该肿瘤的治疗方法，并回顾了其显著的临床和病理特征。
