Brûlé G, Haudecoeur G
Arch Int Physiol Biochim. 1982 Oct;90(3):145-58. doi: 10.3109/13813458209070565.
1.--The tetraethylammonium (TEA) effects on K+ contracture and membrane depolarization are compared in both crab and frog skeletal muscle fibres. 2.--The mechanical tension of the contracture is reduced by the TEA in frog skeletal muscle fibre; it is increased in crab skeletal fibre. 3.--When no mechanical phenomenon is observed in frog skeletal muscle, the amplitude and the velocity of membrane depolarization induced by an increase of outward K+ concentration is reduced by the TEA. These effects are in opposition in crab muscle fibre. 4.--In crab muscle fibre, the results obtained tend to show that the C1-ions are not distributed on each side of the membrane according to Donnan equilibrium.
比较了四乙铵(TEA)对蟹和青蛙骨骼肌纤维钾离子挛缩及膜去极化的影响。
TEA可降低青蛙骨骼肌纤维挛缩的机械张力;而在蟹骨骼肌纤维中则使其增加。
当青蛙骨骼肌未观察到机械现象时,TEA可降低因细胞外钾离子浓度升高引起的膜去极化的幅度和速度。这些效应在蟹肌纤维中则相反。
在蟹肌纤维中,所得结果倾向于表明氯离子并非按照唐南平衡分布于膜的两侧。