Requirement of at least two distinct monoclonal antibodies for efficient neutralization of tetanus toxin in vivo.

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作者信息

Mizuguchi J, Yoshida T, Sato Y, Nagaoka F, Kondo S, Matuhasi T

出版信息

Naturwissenschaften. 1982 Dec;69(12):597-8. doi: 10.1007/BF00396359.

DOI:10.1007/BF00396359

PMID:6186924

Abstract

摘要

相似文献

Requirement of at least two distinct monoclonal antibodies for efficient neutralization of tetanus toxin in vivo.

Naturwissenschaften. 1982 Dec;69(12):597-8. doi: 10.1007/BF00396359.

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Protection of mice against tetanus toxin by combination of two human monoclonal antibodies recognizing distinct epitopes on the toxin molecule.通过两种识别毒素分子上不同表位的人单克隆抗体联合使用来保护小鼠免受破伤风毒素侵害。

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Neutralization of tetanus toxin by distinct monoclonal antibodies binding to multiple epitopes on the toxin molecule.通过与破伤风毒素分子上多个表位结合的不同单克隆抗体对破伤风毒素进行中和。

Infect Immun. 1984 Sep;45(3):604-9. doi: 10.1128/iai.45.3.604-609.1984.

Monoclonal antibodies as probes of tetanus toxin structure and function.单克隆抗体作为破伤风毒素结构与功能的探针

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Characteristics of toxin-neutralization by anti-tetanus human monoclonal antibodies directed against the three functional domains [A], [B] and [C] of the tetanus toxin molecule and a reliable method for evaluating the protective effects of monoclonal antibodies.针对破伤风毒素分子的三个功能域[A]、[B]和[C]的抗破伤风人单克隆抗体的毒素中和特性以及评估单克隆抗体保护作用的可靠方法。

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Quantitation of commercial equine tetanus antitoxin by competitive enzyme-linked immunosorbent assay.通过竞争性酶联免疫吸附测定法定量商业马破伤风抗毒素

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引用本文的文献

Monoclonal antibodies as probes of tetanus toxin structure and function.单克隆抗体作为破伤风毒素结构与功能的探针

Infect Immun. 1983 Dec;42(3):942-8. doi: 10.1128/iai.42.3.942-948.1983.

Infect Immun. 1984 Sep;45(3):604-9. doi: 10.1128/iai.45.3.604-609.1984.

Monoclonal antibodies against tetanus toxin and toxoid.抗破伤风毒素和类毒素的单克隆抗体。

Med Microbiol Immunol. 1983;172(2):123-35. doi: 10.1007/BF02124513.

Expression of tetanus toxin subfragments in vitro and characterization of epitopes.破伤风毒素亚片段的体外表达及表位特征分析

Infect Immun. 1989 Nov;57(11):3498-505. doi: 10.1128/iai.57.11.3498-3505.1989.

Antibodies against the light chain of tetanus toxin in human sera.人血清中抗破伤风毒素轻链的抗体。

Infect Immun. 1985 Jul;49(1):111-5. doi: 10.1128/iai.49.1.111-115.1985.

Establishment of stable mouse/human-human hybrid cell lines producing large amounts of anti-tetanus human monoclonal antibodies with high neutralizing activity.建立稳定的小鼠/人-人杂交细胞系，该细胞系可产生大量具有高中和活性的抗破伤风人单克隆抗体。

Eur J Epidemiol. 1990 Dec;6(4):386-97. doi: 10.1007/BF00151713.

本文引用的文献

SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.体外成纤维细胞交配产生的杂种及其假定重组体的选择

Science. 1964 Aug 14;145(3633):709-10. doi: 10.1126/science.145.3633.709.

Studies on adjuvants for human prophylactics. I. Comparison of efficiencies of different adjuvants at various stages of immunization with tetanus and diphtheria toxoids.人类预防性疫苗佐剂的研究。I. 破伤风类毒素和白喉类毒素免疫不同阶段不同佐剂的效果比较

Jpn J Med Sci Biol. 1978 Jun;31(3):263-76. doi: 10.7883/yoken1952.31.263.

A better cell line for making hybridomas secreting specific antibodies.一种用于制备分泌特异性抗体的杂交瘤的更好的细胞系。

Nature. 1978 Nov 16;276(5685):269-70. doi: 10.1038/276269a0.

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