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Neurotransmitter functions in depression.

作者信息

Lapierre Y D

出版信息

Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(4-6):639-44. doi: 10.1016/s0278-5846(82)80160-7.

DOI:10.1016/s0278-5846(82)80160-7
PMID:6187047
Abstract
  1. Subgroups of depressions may be identified and treated based on MHPG execution. 2. HVA correlates more with activity than with mood. 3. CSF-5HIAA may be helpful in categorising some depressions. 4. Acetylcholine has some effect on mood most probably through indirect action on other neurotransmitters. 5. GABA is still not adequately investigated. 6. Desensitization of presynaptic adrenergic autoreceptors may explain some of the mechanisms of antidepressant action of drugs. 7. Decreased post-synaptic adrenergic activity is a common effect of most antidepressants and of ECT.
摘要

相似文献

1
Neurotransmitter functions in depression.
Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(4-6):639-44. doi: 10.1016/s0278-5846(82)80160-7.
2
[Critical view of biochemical factors in depressive syndromes and the prescription of antidepressants].[对抑郁综合征生化因素及抗抑郁药处方的批判性观点]
Ann Med Psychol (Paris). 1982 Feb;140(2):240-51.
3
[Biologic markers and prediction of response to treatment in depression].[抑郁症的生物学标志物与治疗反应预测]
Acta Psychiatr Belg. 1982 May-Jun;82(3):229-42.
4
[Respective position of antidepressants in therapeutics (author's transl)].
Encephale. 1979;5(5 Suppl):701-8.
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Effect of vagus nerve stimulation on cerebrospinal fluid monoamine metabolites, norepinephrine, and gamma-aminobutyric acid concentrations in depressed patients.迷走神经刺激对抑郁症患者脑脊液单胺代谢产物、去甲肾上腺素和γ-氨基丁酸浓度的影响。
Biol Psychiatry. 2004 Sep 15;56(6):418-26. doi: 10.1016/j.biopsych.2004.06.025.
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Monoamine metabolites as predictors of antidepressant response: a critique.单胺代谢物作为抗抑郁反应的预测指标：一项批判性分析。
Prog Neuropsychopharmacol Biol Psychiatry. 1983;7(2-3):229-40. doi: 10.1016/0278-5846(83)90113-6.
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Biological quantitative methods in the evaluation of psychiatric treatment: some biochemical criteria.
Neuropsychobiology. 1982;8(2):60-72. doi: 10.1159/000117879.
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[Biochemistry of depression and antidepressants].
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Neurochemical variables in subjects with adjustment disorder after suicide attempts.自杀未遂后患有适应障碍的受试者的神经化学变量。
Eur Psychiatry. 2000 May;15(3):190-5. doi: 10.1016/s0924-9338(00)00226-1.
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