使用水溶性分枝杆菌组分诱导变应性脑脊髓炎。
Induction of allergic encephalomyelitis using hydrosoluble mycobacterial fractions.
作者信息
Westall F C, Thompson M, Migliore-Samour D, Jollés P
出版信息
Eur J Immunol. 1976 Jul;5(7):504-5. doi: 10.1002/eji.1830050715.
PMID:61873
Abstract
Experimental allergic encephalomyelitis has been induced in guinea pigs employing bovine myelin basic protein as the antigen and a hydrosoluble tetrasaccharide-heptapeptide from delipidated cells of the human mycobacterial strain H37Ra as adjuvant. The maximum response was observed using 33 mug of antigen and 12.5 mug of adjuvant per animal.
摘要
以牛髓磷脂碱性蛋白为抗原，用人结核杆菌H37Ra脱脂细胞的一种水溶性四糖 - 七肽作为佐剂，在豚鼠中诱发了实验性变应性脑脊髓炎。每只动物使用33微克抗原和12.5微克佐剂时观察到最大反应。
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