四种P物质相关拮抗剂的药理学特性 - Suppr

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Pharmacological characterization of four related substance P antagonists.

作者信息

Björkroth U, Rosell S, Xu J C, Folkers K

出版信息

Acta Physiol Scand. 1982 Oct;116(2):167-73. doi: 10.1111/j.1748-1716.1982.tb07126.x.

DOI:10.1111/j.1748-1716.1982.tb07126.x

PMID:6188324

Abstract

摘要

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Pharmacological characterization of four related substance P antagonists.四种P物质相关拮抗剂的药理学特性

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[The effect of hydrogen-ion concentration, calcium concentration and temperature on the contraction of guinea pig ileum induced by eledoisin and eledoisin peptides. A contribution on the action mechanism of these peptides].[氢离子浓度、钙浓度及温度对eledoisin和eledoisin肽诱导的豚鼠回肠收缩的影响。对这些肽作用机制的研究]

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Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea.用于P物质的十一肽和八肽拮抗剂：豚鼠气管研究

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Contractile responses to substance P and related peptides of the isolated muscularis mucosae of the guinea-pig oesophagus.豚鼠食管离体黏膜肌层对P物质及相关肽的收缩反应。

Br J Pharmacol. 1984 Jan;81(1):143-9. doi: 10.1111/j.1476-5381.1984.tb10754.x.

Development of a new tachykinin antagonist.一种新型速激肽拮抗剂的研发。

Experientia. 1984 Jan 15;40(1):86-8. doi: 10.1007/BF01959116.

Functional characterization of substance P receptors in the rabbit ear artery.兔耳动脉中P物质受体的功能特性

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Blockade of slow excitatory post-synaptic potential by substance P antagonists in guinea-pig sympathetic ganglia.P物质拮抗剂对豚鼠交感神经节慢兴奋性突触后电位的阻断作用

J Physiol. 1985 Apr;361:115-30. doi: 10.1113/jphysiol.1985.sp015636.

Presence of a substance P-like peptide in an acid extract of the intestinal bulb of the carp (Cyprinus carpio).鲤鱼（鲤属鲤科）肠球部酸提取物中存在P物质样肽。

Br J Pharmacol. 1988 Sep;95(1):39-48. doi: 10.1111/j.1476-5381.1988.tb16546.x.

Autonomic, sensory, and motor dysfunction following intrathecal administration of three substance P antagonists.

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J Physiol. 1987 Aug;389:69-97. doi: 10.1113/jphysiol.1987.sp016647.

Effect of the tachykinin antagonist, [D-Pro4, D-Trp7,9,10] substance P-(4-11), on tachykinin- and histamine-induced inositol phosphate generation in intestinal smooth muscle.速激肽拮抗剂[D-脯氨酸4，D-色氨酸7,9,10]P物质-(4-11)对速激肽和组胺诱导的肠平滑肌肌醇磷酸生成的影响。

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