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从鼓室上隐窝清除积液物质——大鼠实验研究

Clearance of effusion material from the attic space--an experimental study in the rat.

作者信息

Albiin N, Hellström S, Stenfors L E

出版信息

Int J Pediatr Otorhinolaryngol. 1983 Jan;5(1):1-10. doi: 10.1016/s0165-5876(83)80002-0.

DOI:10.1016/s0165-5876(83)80002-0
PMID:6188709
Abstract

Rat serum with Evan's blue added as a tracer was instilled into the attic through a pars flaccida perforation in rats. At intervals the drainage of the effusion-like material was observed through a hole in the tympanic bulla. The distribution of ciliary cells was studied in the middle ear using light microscopic and scanning electronmicroscopic techniques. It was noted that the effusion material was propelled from the attic to the inlet of the Eustachian tube mainly by hydrostatic forces. It is also concluded that this mechanism might apply in Homo sapiens and that the drainage position of the head may be of importance in preventing and treating otitis media with effusion (OME).

摘要

将添加伊文思蓝作为示踪剂的大鼠血清通过大鼠松弛部穿孔注入鼓室上隐窝。每隔一段时间,通过鼓泡上的一个孔观察类似积液物质的引流情况。使用光学显微镜和扫描电子显微镜技术研究中耳中纤毛细胞的分布。值得注意的是,积液物质主要通过流体静力从鼓室上隐窝被推进到咽鼓管入口。还得出结论,这种机制可能适用于人类,并且头部的引流位置在预防和治疗分泌性中耳炎(OME)中可能很重要。

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