晶状体分化。小牛晶状体分离上皮中的晶状体蛋白合成。
Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses.
作者信息
Vermorken A J, Hilderink J M, van de Ven W J, Bloemendal H
出版信息
J Cell Biol. 1978 Jan;76(1):175-83. doi: 10.1083/jcb.76.1.175.
Abstract
In the calf eye lens, four morphologically distinct cell types can be detected: three in the epithelial monolayer and one in the cortical part. During differentiation, there is a quantitative change in the synthesis of crystallin subunits. A marked increase in alphaA-chains and several beta-crystallin polypeptides accompanies the transition from epithelial to fiberlike lens cells while synthesis of the non-crystallin proteins diminishes significantly.
摘要
在小牛眼晶状体中，可以检测到四种形态上不同的细胞类型：上皮单层中有三种，皮质部分有一种。在分化过程中，晶状体蛋白亚基的合成发生了定量变化。从上皮细胞向纤维状晶状体细胞转变时，αA链和几种β晶状体蛋白多肽显著增加，而非晶状体蛋白的合成则显著减少。
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