Bryson S C
Am J Obstet Gynecol. 1983 May 15;146(2):163-5. doi: 10.1016/0002-9378(83)91046-3.
This prospective study shows that the beta-subunit of human chorionic gonadotropin (beta-hCG) "screen" and ultrasound provide for nearly 100% clinical accuracy in diagnosing ectopic pregnancy in suspected cases. During the 14 months from February, 1981, to April, 1982, 81 consecutive patients believed to have ectopic pregnancies were screened. Fifty-six had a negative beta-hCG screen, thus ruling out early pregnancy complications. No false negative results were found. Twenty-seven patients had a positive screen, and 16 of these had an ectopic pregnancy. Twenty of the 27 patients with a positive beta-hCG screen underwent pelvic ultrasound examination. All of those with a positive beta-hCG screen and no intrauterine pregnancy on ultrasound had ectopic pregnancies. With the use of these clinical aids, morbidity and tubal damage are reduced because delay in operating upon those with ectopic pregnancy is avoided. Unnecessary operation is avoided in those patients who do not have an ectopic pregnancy.
这项前瞻性研究表明，人绒毛膜促性腺激素β亚基（β-hCG）“筛查”和超声检查在疑似病例中诊断异位妊娠的临床准确率接近100%。在1981年2月至1982年4月的14个月期间，对连续81例被认为患有异位妊娠的患者进行了筛查。56例β-hCG筛查为阴性，从而排除了早期妊娠并发症。未发现假阴性结果。27例筛查为阳性，其中16例患有异位妊娠。27例β-hCG筛查为阳性的患者中有20例接受了盆腔超声检查。所有β-hCG筛查为阳性且超声检查未发现宫内妊娠的患者均患有异位妊娠。通过使用这些临床辅助手段，由于避免了对异位妊娠患者的手术延迟，发病率和输卵管损伤得以降低。对于没有异位妊娠的患者，避免了不必要的手术。
