Morganti P, Bruno C, Colelli G
Boll Soc Ital Biol Sper. 1983 Jan 31;59(1):20-5.
It is known how noticeable modifications may be induced in the high sulphur content proteins of wool, by enrichment of the diet of sheep with cysteine or sulphur amino acids. It is also well known how the oral ingestion of gelatin significantly increases hair diameter and the degree of hardness of finger and toe nails. To the end of verifying the possible stimulating selective action performed by cystine and gelatin in the keratinization processes of the hairy structures, it was controlled: amino acids content in hair of normal rat after oral ingestion of a controlled quantity of gelatin-cystine added in the diet. The same experiments have been carried out on rats in which the condition of sufference of the hair was induced by means of a biotin-free diet. From the obtained data it seems that gelatin-cystine, added in the diet of normal or suffering rats, helps to modify the cysteine content of the sulphur-rich hair proteins (+ 50% abt.). The diet supplement bring about a considerable increasing of CYS (+ 35%) with a decreasing of GLY (- 15%).
众所周知,通过用半胱氨酸或含硫氨基酸丰富绵羊的饮食,可以在羊毛的高硫含量蛋白质中诱导出明显的修饰。同样众所周知的是,口服明胶会显著增加头发直径以及手指甲和脚趾甲的硬度。为了验证胱氨酸和明胶在毛发结构角质化过程中可能产生的刺激选择性作用,对正常大鼠口服添加在饮食中的定量明胶 - 胱氨酸后毛发中的氨基酸含量进行了控制。对通过无生物素饮食诱导毛发受损的大鼠也进行了相同的实验。从获得的数据来看,添加在正常或受损大鼠饮食中的明胶 - 胱氨酸有助于改变富含硫的毛发蛋白质中的半胱氨酸含量(约增加50%)。饮食补充剂使半胱氨酸显著增加(增加35%),同时甘氨酸减少(减少15%)。