特应性哮喘中的血浆接触系统
The plasma contact system in atopic asthma.
作者信息
Lasser E C, Lang J H, Curd J G, Cochrane C G, Lyon S G, Howard M M, Hamblin A E, Revak S D
出版信息
J Allergy Clin Immunol. 1983 Jul;72(1):83-8. doi: 10.1016/0091-6749(83)90056-8.
PMID:6189880
Abstract
An in vitro test for the rate of appearance of kallikrein in plasma due to contact system activation by dextran sulfate at 0 degree C was applied to plasmas of 19 atopic asthma patients and 19 age- and sex-matched controls without atopy. The average prekallikrein activation rate was markedly higher in the plasmas of the atopic patients. Mean endogenous heparin levels were also elevated.
摘要
应用一种体外试验，检测在0摄氏度下硫酸葡聚糖激活接触系统后血浆中激肽释放酶的出现速率，该试验应用于19名特应性哮喘患者和19名年龄及性别匹配的非特应性对照者的血浆。特应性患者血浆中的前激肽释放酶平均激活率明显更高。内源性肝素水平也升高。
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