Christodoulou G N
J Nerv Ment Dis. 1978 Jan;166(1):68-72.
The course and prognosis of 20 patients with the syndrome of doubles (syndrome of Capgras, syndrome of Frégoli, syndrome of intermetamorphosis, syndrome of subjective doubles) were studied. The onset of the syndrome occurred either synchronously or at a later stage than the onset of the associated psychosis. The syndrome failed to remit in seven of the 20 cases, and in the others remission occurred either synchronously with or later than the remission of the basic psychosis. In all cases of depression, the syndrome cleared shortly after remission of the depressive illness. It was, however, more persistent than the accompanying psychosis in the schizophrenic patients with the Capgras variety. Relapse of the basic psychotic condition in the setting of which the syndrome had originally developed was invariably accompanied by reappearance of the syndrome.
对20例替身综合征（卡普格拉综合征、弗雷戈里综合征、变身综合征、主观替身综合征）患者的病程及预后进行了研究。该综合征的起病与相关精神病的起病同步或较晚出现。20例中有7例该综合征未缓解，其他病例的缓解与基础精神病的缓解同步或较晚出现。在所有抑郁症病例中，该综合征在抑郁性疾病缓解后不久即消失。然而，在患有卡普格拉型的精神分裂症患者中，该综合征比伴随的精神病更持久。最初出现该综合征的基础精神病病情复发时，该综合征总是会再次出现。
