Pamperl H, Kleinberger G, Meryn S
Leber Magen Darm. 1982 Oct;12(5):213-6.
Increased levels of serum amylase were found in 14 out of 34 patients (41%) with coma due to acute liver failure, in 8 out of 55 patients (14%) with hepatic encephalopathy, and in 5 out of 10 patients with a mixed pathogenesis. In 4 patients of the first group (11.7%) and 4 of the second group (7%) pancreatitis was diagnosed at post mortem. The pathogenesis of pancreatitis concomitant with liver failure is unclear. Virus infection and intoxication may do damage to both organs; hemodynamic factors, coagulation defects, and derangements of metabolism may play a role as well.
在34例急性肝衰竭所致昏迷患者中,14例(41%)血清淀粉酶水平升高;在55例肝性脑病患者中,8例(14%)升高;在10例具有混合病因的患者中,5例升高。第一组中有4例患者(11.7%),第二组中有4例患者(7%)在尸检时被诊断为胰腺炎。肝衰竭合并胰腺炎的发病机制尚不清楚。病毒感染和中毒可能对两个器官都造成损害;血流动力学因素、凝血缺陷和代谢紊乱也可能起作用。