Vinik A I, Achem-Karam S, Owyang C
Spec Top Endocrinol Metab. 1982;4:93-138.
Information concerning GEP hormones has progressively advanced since the initial discovery of a GEP hormone, secretin, in 1902. Studies in this area flourished with the advent of radioimmunoassay, and have provided an understanding of the secretion, regulation, metabolic actions, and role in certain diseases of major GEP hormones. Measurement of GEP hormones has achieved importance in clinical medicine and allowed understanding of the pathophysiology of several clinical disorders. The decade to come should witness additional advances in this rapidly expanding field.
自1902年首次发现胃肠胰(GEP)激素促胰液素以来,有关GEP激素的信息不断取得进展。随着放射免疫测定法的出现,该领域的研究蓬勃发展,并使人们对主要GEP激素的分泌、调节、代谢作用及其在某些疾病中的作用有了认识。GEP激素的测定在临床医学中已变得至关重要,并有助于理解多种临床病症的病理生理学。在这个迅速发展的领域,未来十年有望见证更多进展。