De Tribolet N
Bull Schweiz Akad Med Wiss. 1981:113-21.
Immunological markers of human gliomas have been looked for by studying the patient's immune response or by raising heteroantisera against these tumours. More recently, the hybridoma technology has allowed to produce monoclonal antibodies recognizing a single antigenic determinant. This paper describes the production of monoclonal antibodies against human glioma-associated antigens and discusses their possible applications as diagnostic tools.
通过研究患者的免疫反应或制备针对这些肿瘤的异种抗血清,人们一直在寻找人类胶质瘤的免疫标志物。最近,杂交瘤技术已能够产生识别单一抗原决定簇的单克隆抗体。本文描述了针对人类胶质瘤相关抗原的单克隆抗体的产生,并讨论了它们作为诊断工具的可能应用。