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病态肥胖胃成形术后出现类似酒精性透明样变的肝损伤。

Liver injury with alcoholiclike hyalin after gastroplasty for morbid obesity.

作者信息

Hamilton D L, Vest T K, Brown B S, Shah A N, Menguy R B, Chey W Y

出版信息

Gastroenterology. 1983 Sep;85(3):722-6.

PMID:6192039
Abstract

Hepatic damage resembling alcoholic hepatitis has been described after jejunoileal bypass surgery for morbid obesity, but has not been previously reported as a complication of gastric partitioning operations (gastric bypass and gastroplasty). A patient who developed an alcoholic hepatitislike clinical picture 8 mo after gastroplasty is described, suggesting that malnutrition superimposed on obesity may be responsible for the injury in both settings. Reversal of the gastroplasty was associated with clinical and biochemical improvement.

摘要

空肠回肠旁路手术治疗病态肥胖后曾有类似酒精性肝炎的肝损伤报道,但此前尚未见其作为胃分隔手术(胃旁路术和胃成形术)并发症的报告。本文描述了1例胃成形术8个月后出现类似酒精性肝炎临床表现的患者,提示肥胖叠加营养不良可能是两种情况下肝损伤的原因。胃成形术的逆转与临床及生化指标的改善相关。

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