Probst P, Mühlberger V, Lederbauer M, Pachinger O, Kaliman J, Steinbach K
Pacing Clin Electrophysiol. 1983 Jul;6(4):689-96. doi: 10.1111/j.1540-8159.1983.tb05327.x.
Thirty patients with carotid sinus syndrome were electrophysiologically studied. In 14 patients carotid sinus massage was performed during atrial and ventricular stimulation, and the conduction times were measured. The AH-time was prolonged by more than 120 ms in 6 patients (20%); the HV-time was prolonged in 6 patients by more than 55 ms (20%); 5 patients had bundle branch block (16.7%); The sinus node recovery time was prolonged in 7 out of 27 patients (26%). Ten patients (33%) did not have additional electrophysiologic abnormalities. There was a predominance of carotid sinus syndrome on the right side. During carotid sinus massage there was a significant increase of the AH-time, but there were no significant changes of the HV-time or the width of the QRS-complexes. Twenty-one patients developed an atrial asystole and 9 patients an atrial bradycardia and an additional AV-block. There was a longer AH-time and a longer prolongation of the AH-time in the patients who developed an AV-block. Twelve out of 14 patients (85.7%) developed an AV-block during carotid sinus massage and atrial pacing. During ventricular pacing 5 of 14 patients (35.7%) revealed a complete retrograde block before carotid sinus massage and 5 of the remaining 9 patients developed a total retrograde block during carotid sinus massage. Consequently, in 71.4% of the patients with carotid sinus syndrome complete retrograde conduction block and atrial asystole can be expected during attacks of ventricular asystole and simultaneous ventricular pacing. In conclusion, there is a high incidence of additional disturbances of the sinus node function and AV-conduction in patients with carotid sinus syndrome. AAI pacemakers are contraindicated due to the common development of additional AV-block during carotid sinus massage. Physiologic pacing might contribute to better hemodynamics, particularly in patients with the mixed type of carotid sinus syndrome.
对30例颈动脉窦综合征患者进行了电生理研究。14例患者在心房和心室刺激期间进行了颈动脉窦按摩,并测量了传导时间。6例患者(20%)的AH间期延长超过120毫秒;6例患者(20%)的HV间期延长超过55毫秒;5例患者(16.7%)有束支传导阻滞;27例患者中有7例(26%)窦房结恢复时间延长。10例患者(33%)没有其他电生理异常。颈动脉窦综合征以右侧为主。颈动脉窦按摩期间AH间期显著增加,但HV间期或QRS波群宽度无显著变化。21例患者出现心房停搏,9例患者出现心房心动过缓和附加的房室传导阻滞。发生房室传导阻滞的患者AH间期更长且AH间期延长更明显。14例患者中有12例(85.7%)在颈动脉窦按摩和心房起搏期间出现房室传导阻滞。心室起搏期间,14例患者中有5例(35.7%)在颈动脉窦按摩前显示完全性逆行传导阻滞,其余9例患者中有5例在颈动脉窦按摩期间出现完全性逆行传导阻滞。因此,在71.4%的颈动脉窦综合征患者中,预计在心室停搏发作和同步心室起搏期间会出现完全性逆行传导阻滞和心房停搏。总之,颈动脉窦综合征患者中窦房结功能和房室传导的附加紊乱发生率很高。由于在颈动脉窦按摩期间常发生附加的房室传导阻滞,AAI起搏器是禁忌的。生理性起搏可能有助于改善血流动力学状况,特别是对于混合型颈动脉窦综合征患者。