Charpin J, Arnaud A
Rev Fr Mal Respir. 1983;11(4):397-407.
The problem of occupational asthma is in state of change as evidenced by the official reports: The official Journal of the 23 January 1982 contains important alterations in the lists of occupational asthma, changing some and creating others, as with table 66 in which numerous occupational allergies are listed. The authors discuss current diagnostic methods in which realistic provocation tests play an important part; current causes are considered and are duly allocated between natural animal or vegetable products or chemicals produced by industry. The authors strive to define which aetiologies are declining and which remain every day problems. Occupational asthma should be treated at source though the offending agent is not always apparent. The mechanism may be allergic, or often non allergic histamine-liberation or other pharmacodynamic mechanisms. Finally, the understanding of occupational asthmas throws light on the mechanism of asthma itself.
职业性哮喘问题正处于变化之中，官方报告可证明这一点：1982年1月23日的官方期刊中，职业性哮喘清单有重大变动，一些内容更改，另一些则新增，如表66列出了众多职业性过敏。作者讨论了当前的诊断方法，其中现实的激发试验起着重要作用；考量了当前的病因，并在天然动植物产品或工业生产的化学品之间进行了适当分配。作者努力确定哪些病因在减少，哪些仍是日常问题。尽管致病因素并不总是显而易见，但职业性哮喘应从源头进行治疗。其机制可能是过敏性的，或通常是非过敏性组胺释放或其他药效学机制。最后，对职业性哮喘的认识有助于阐明哮喘本身的机制。
