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[人类银染染色体核仁组织区群体多态性的比较分析]

[Comparative analysis of the population polymorphism of human silver-staining chromosomal nucleolus organizer regions].

作者信息

Kristesashvili D I, Beniush V A, Egolina N A, Davudov A Z

出版信息

Genetika. 1983 Jul;19(7):1205-9.

PMID:6194045
Abstract

The population study of nucleus organizing regions (NOR) activity in individuals of Georgian nationality was carried out using the Ag-method. The results obtained were compared with those for other populations: Russian, Viena-Ulm, Estonian etc. The mean number of active NORs for Georgians is 9.0, which significantly exceeds analogous indexes for the rest of populations, except Viena-Ulm one. The population differences in the distribution of NOR activity and the ability to be stained was found for individual NORs. The lowest activity was registered in chromosome 14, the highest being observed for chromosomes 21 and 13. It is assumed that some mechanism exists that controls the level of general NOR activity in the cell.

摘要

采用银染法对格鲁吉亚族个体的核仁组织区(NOR)活性进行了群体研究。将所得结果与其他群体(俄罗斯族、维也纳 - 乌尔姆族、爱沙尼亚族等)的结果进行了比较。格鲁吉亚族人的活跃NORs平均数量为9.0,除维也纳 - 乌尔姆族外,这一数值显著高于其他群体的类似指标。研究发现,个体NORs在NOR活性分布和染色能力方面存在群体差异。在14号染色体上观察到最低活性,而在21号和13号染色体上活性最高。据推测,细胞中存在某种控制总体NOR活性水平的机制。

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