Schäbitz J, Petri A
Folia Haematol Int Mag Klin Morphol Blutforsch. 1983;110(2):301-8.
In 21 cases the blood viscosity of native blood was determined in comparison to heparin blood at a shear rate of 218.7 and 1312 sec-1 by using the rotational viscosimeter Rheotest 2. As a result, a low viscosity of the heparin blood could be found. In addition, the impact of phenprocoumon treatment on several rheologic parameters was examined in 20 healthy test persons. With the haematocrit and fibrinogen level remaining constant, a reduction of blood viscosity could be observed when the Quick value decreased. This was detected with Rheotest 2 at 7 different shear rate between 218.7 and 1312 sec-1. The influence of anticoagulants on the erythrocyte deformability is discussed as a possible cause underlying the obtained decreases of viscosity. This would have to be proved by investigations using erythrocyte filters.
使用Rheotest 2旋转粘度计，在218.7和1312秒⁻¹的剪切速率下，对21例患者的全血粘度与肝素化血液的粘度进行了比较测定。结果发现，肝素化血液的粘度较低。此外，对20名健康受试者进行了苯丙香豆素治疗对多个流变学参数影响的研究。在血细胞比容和纤维蛋白原水平保持恒定的情况下，当Quick值降低时，可观察到血液粘度降低。这是在218.7至1312秒⁻¹之间的7种不同剪切速率下用Rheotest 2检测到的。抗凝剂对红细胞变形性的影响被讨论为所观察到的粘度降低的可能原因。这必须通过使用红细胞滤器的研究来证实。
