Burger G, Jütting U, Soost H J
Microsc Acta Suppl. 1983;6:103-20.
Analytical and quantitative cytology is based upon photometric and morphometric measurements of single cells in stained cytological specimens. It analyzes the features of single cells and cell populations with respect to their cytodiagnostic relevance. One way to do this is the establishment of learning sets of visually selected cells, and the intercomparison of unknown cells with these data sets. Difficulties arise with the visual classification of single cells from PAP-stained gynecological smears and the pooling into classes due to the considerable photometric variation from specimen to specimen. It is demonstrated, that neither for a cancer prescreening apparatus nor an interactive diagnostic machine, highly differentiated learning sets can be dispensed with. The build-up of the TUDAB learning sets and results of single cell classification, visual reclassification, as well as population analysis and specimen classification are shown.
分析性和定量细胞学基于对染色细胞学标本中单个细胞的光度测量和形态测量。它从细胞诊断相关性方面分析单个细胞和细胞群体的特征。一种方法是建立视觉选择细胞的学习集,并将未知细胞与这些数据集进行相互比较。由于巴氏染色的妇科涂片标本之间存在相当大的光度变化,对单个细胞进行视觉分类并将其归为不同类别存在困难。结果表明,无论是癌症预筛查设备还是交互式诊断机器,都离不开高度分化的学习集。展示了图达布(TUDAB)学习集的构建以及单细胞分类、视觉重新分类、群体分析和标本分类的结果。