Arslan Pagnini C, Rugge M
Histopathology. 1983 Sep;7(5):699-706. doi: 10.1111/j.1365-2559.1983.tb02282.x.
Intestinal metaplasia in the mucosa adjacent to a gastric carcinoma suggests that some carcinomas of the stomach might arise from metaplastic mucosa, as well as the existence of a gastric cancer with morphological features resembling intestinal mucosa. In this study, the extent of intestinal metaplasia of adjacent mucosa, the type of intestinal metaplasia (complete or incomplete), the degree of tumour differentiation, the type and quantity of mucins secreted by neoplastic cells and morphological features of the tumours were evaluated in 59 cases of gastric carcinoma. An analysis of the findings suggests that a carcinoma may arise in the stomach with features of association with incomplete metaplasia and histochemical and histological patterns which mimic carcinomas of the large intestine.
胃癌旁黏膜的肠化生提示，部分胃癌可能起源于化生黏膜，也提示存在形态学特征类似肠黏膜的胃癌。本研究评估了59例胃癌患者癌旁黏膜的肠化生范围、肠化生类型（完全型或不完全型）、肿瘤分化程度、肿瘤细胞分泌的黏蛋白类型和数量以及肿瘤的形态学特征。对研究结果的分析表明，胃内可能发生具有不完全化生相关特征以及类似大肠癌组织化学和组织学模式的癌。
