Wilmes E, Deinhardt F
Arch Otorhinolaryngol Suppl. 1983;1:1-112.
Viral infections cause many disease in the mucous membranes, the upper respiratory and digestive tract, the salivary glands and the ear. Recent advances in the pathogenesis of viral diseases brought about an increasing interest of otolaryngologists. The general part of this paper presents the fundamental properties of viruses, their structure and replication, and the pathogenesis of the different forms of viral infections. The section of viral diagnosis describes laboratory methods and their limits as well as the clinical interpretation of viral tests. An overview of viral diagnosis describes laboratory methods and their limits as well as the clinical interpretation of viral test. An overview of prophylaxis and therapy of viral infections is given. The specialized section of the paper describes viral infections important for the otorhinolaryngologist. It includes infections of the aero-digestive tract, the ear and the salivary glands. Because of its special importance, Epstein-Barr virus and its associated diseases, and hypotheses about the oncogenesis of EBV-correlated tumours are presented in detail. The topic of the third part is of actual knowledge about interferon and its antiviral and antitumour effects. The findings of important clinical studies are discussed. The last chapter concerns with virushepatitis.
病毒感染可引发黏膜、上呼吸道和消化道、唾液腺及耳部的多种疾病。病毒疾病发病机制的最新进展引发了耳鼻喉科医生越来越浓厚的兴趣。本文的总论部分介绍了病毒的基本特性、结构与复制,以及不同形式病毒感染的发病机制。病毒诊断部分描述了实验室方法及其局限性,以及病毒检测的临床解读。概述了病毒感染的预防和治疗。本文的专门章节描述了对耳鼻喉科医生而言重要的病毒感染。包括空气消化道、耳部和唾液腺的感染。由于其特殊重要性,详细介绍了爱泼斯坦-巴尔病毒及其相关疾病,以及关于EBV相关肿瘤肿瘤发生的假说。第三部分的主题是关于干扰素及其抗病毒和抗肿瘤作用的实际知识。讨论了重要临床研究的结果。最后一章涉及病毒性肝炎。