Moore G R, Robertson D M, Boegman R J
Brain Res. 1983 Nov 21;279(1-2):246-9. doi: 10.1016/0006-8993(83)90185-3.
Batrachotoxin (BTX), when applied to peripheral nerve in concentrations sufficient to block impulse transmission and axonal transport, causes axonal necrosis. Quantitation of this phenomenon reveals reduction of both myelinated and unmyelinated fibers 7 days post-BTX injection. Evidence for regeneration correlates with the previously reported recovery of postsynaptic events.
将足以阻断冲动传导和轴突运输的浓度的箭毒蛙毒素(BTX)应用于外周神经时,会导致轴突坏死。对这一现象进行定量分析发现,在注射BTX后7天,有髓纤维和无髓纤维均减少。再生的证据与先前报道的突触后事件的恢复相关。