箭毒蛙毒素抑制加利福尼亚海兔单个神经元的轴突运输，而不影响其膜电位。
Batrachotoxin inhibits axonal transport without affecting membrane potential in single neurons of Aplysia californica.
作者信息
Kumara-Siri M H
出版信息
J Neurobiol. 1979 Sep;10(5):509-12. doi: 10.1002/neu.480100508.
PMID:90717
Abstract
Intrasomatic injection of 0.25 ng of batrachotoxin (BTX) caused no depolarization of giant cerebral neurons (GCN) of Aplysia californica within 4 hr at 23 degrees C. The amplitude of action potential and the input resistance were slightly and reversibly decreased. The same dose of BTX caused a 68% inhibition of fast axonal transport.
摘要
在23摄氏度下，向海兔（Aplysia californica）体内注射0.25纳克的箭毒蛙毒素（BTX），在4小时内未引起巨大脑神经元（GCN）去极化。动作电位的幅度和输入电阻略有下降且可逆转。相同剂量的BTX导致快速轴突运输受到68%的抑制。
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