Combined treatment of maxillofacial carcinoma by intra-arterial proliferation block and irradiation.

We investigated the possible potentiation of a regimen of combined cytostatic and radiation therapy for epidermoid carcinoma of the maxillofacial region. The described combined approach by intra-arterial infusion of ADR and BLM and cytokinetically controlled irradiation was able to produce CR in all treated primary tumors of the head and neck. Regional metastases are not definitely controlled and require surgical intervention.