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[毒性甲状腺肿时甲状腺的激素活性及形态学变化]

[Hormonal activity and morphological changes in the thyroid gland in toxic goiter].

作者信息

Krivitskiĭ D I

出版信息

Vestn Khir Im I I Grek. 1983 Oct;131(10):6-9.

PMID:6197802
Abstract

The Basedow's and basedowified goiter with proliferation of the follicular epithelium was revealed in 82-88% of patients with severe and mild thyreotoxicosis. These patients, as a rule, have high indices of the thyroid hormones in the blood. In patients with a light form of toxic goiter such histological changes were noted in half of the patients, proliferation of the thyroid epithelium was noted only in 25% of cases. Data of comparison of the hormonal and orphological changes in the thyroid gland were used for choosing the volume of resection of the gland. It allowed the incidence of postoperative recurrences of thyreotoxicosis to be reduced to 0,82% and of stable hypothyrosis to 0,75%.

摘要

在82%-88%的重度和轻度甲状腺毒症患者中发现了伴有滤泡上皮增生的Basedow病和类Basedow病甲状腺肿。通常,这些患者血液中的甲状腺激素指标较高。在轻度毒性甲状腺肿患者中,半数患者出现了此类组织学变化,仅25%的病例出现甲状腺上皮增生。甲状腺激素和形态学变化的比较数据被用于确定腺体切除量。这使得甲状腺毒症术后复发率降至0.82%,永久性甲状腺功能减退症发生率降至0.75%。

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