[Hormonal activity and morphological changes in the thyroid gland in toxic goiter].

The Basedow's and basedowified goiter with proliferation of the follicular epithelium was revealed in 82-88% of patients with severe and mild thyreotoxicosis. These patients, as a rule, have high indices of the thyroid hormones in the blood. In patients with a light form of toxic goiter such histological changes were noted in half of the patients, proliferation of the thyroid epithelium was noted only in 25% of cases. Data of comparison of the hormonal and orphological changes in the thyroid gland were used for choosing the volume of resection of the gland. It allowed the incidence of postoperative recurrences of thyreotoxicosis to be reduced to 0,82% and of stable hypothyrosis to 0,75%.