Brettes J P, Tourne C E, Gandar R
J Gynecol Obstet Biol Reprod (Paris). 1976 Jul-Aug;5(5):637-44.
Using an immunological technique limits of normal levels of AFP in maternal blood have been worked out during pregnancy from a series of 3010 samples of blood. Comparing mean curves for the levels of AFP in mothers suffering from anaemia and diabetes with normal curves shows that there is a significant rise in these levels in the third trimester of pregnancy. The possible mechanisms and their relationship to the variation levels of AFP are discussed.
运用免疫技术,从3010份孕妇血样中得出了孕期母血中正常甲胎蛋白水平的限度。将贫血和糖尿病孕妇的甲胎蛋白水平平均曲线与正常曲线进行比较,结果显示在妊娠晚期这些水平有显著升高。文中讨论了可能的机制及其与甲胎蛋白水平变化的关系。