Baker S R, Wheeler R
Head Neck Surg. 1984 Jan-Feb;6(3):751-60. doi: 10.1002/hed.2890060309.
Despite almost 3 decades of experience, the use of intraarterial (IA) chemotherapy for the treatment of head and neck cancer is not universally accepted. The overall reported response rates are not substantially different from the therapeutic results obtained with systemic therapy. The additional complications associated with establishing and maintaining arterial access have further dampened enthusiasm for this approach. It is clear that considerable improvement in the techniques and efficacy of IA chemotherapy is necessary. This second and last part of this article considers the past and present clinical experience with IA therapy in the treatment of head and neck cancer and explores future developments.
尽管有近30年的经验，但动脉内（IA）化疗用于治疗头颈癌并未得到广泛认可。报告的总体缓解率与全身治疗所获得的治疗效果并无显著差异。与建立和维持动脉通路相关的额外并发症进一步削弱了人们对这种方法的热情。显然，IA化疗的技术和疗效需要有相当大的改进。本文的第二部分也是最后一部分将回顾IA治疗头颈癌的过去和现在的临床经验，并探讨未来的发展。
