Loddenkemper R, Gabler A, Göbel D
Thorac Cardiovasc Surg. 1983 Dec;31(6):334-7. doi: 10.1055/s-2007-1022013.
In this prospective study of 433 patients undergoing surgery for bronchial carcinoma 3 main factors influencing the operative risk were identified: (1) extent of resection, (2) pulmonary function and (3) age. The 30-day mortality rate was 8.3% in the whole group which comprised a high percentage of patients over 70 years of age (27%) and with a disturbed pulmonary function (45%). The value of various functional criteria proposed in the extensive literature is assessed and compared with the results of the study in which the use of FEV1 and quantitative regional analysis by perfusion scanning and 'regions of interest' proved to be highly efficient, allowing, in addition, the prediction of postoperative lung function even in sleeve resections. A new formula for estimation of the additional loss of function in the early postoperative phase after lobectomies is proposed along with a flow sheet for routine preoperative evaluation of pulmonary function.
在这项针对433例接受支气管癌手术患者的前瞻性研究中，确定了影响手术风险的3个主要因素：（1）切除范围，（2）肺功能，（3）年龄。整个组的30天死亡率为8.3%，其中70岁以上患者（27%）和肺功能受损患者（45%）占比很高。评估了大量文献中提出的各种功能标准的价值，并将其与本研究结果进行比较。在本研究中，使用第一秒用力呼气量（FEV1）以及灌注扫描和“感兴趣区”进行定量区域分析被证明是非常有效的，此外，即使在袖状切除术中也能预测术后肺功能。提出了一个新的公式，用于估计肺叶切除术后早期额外的功能丧失，并给出了一份肺功能术前常规评估流程表。
