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[小肠黏膜层中的酶]

[Enzymes in the mucosal layer of the small intestine].

作者信息

Bandurko L N, Brodskiĭ R A, Gal'perin Iu M, Lazarev P I

出版信息

Biull Eksp Biol Med. 1984 Feb;97(2):160-3.

PMID:6199054
Abstract

It has been demonstrated by the methods of histochemical and biochemical examination of the activity of the enzymes that the mucus layer covering the small intestinal wall contains active enzymes (alkaline phosphatase, leucin aminopeptidase IV, saccharase, lactase) and pancreatic enzymes (alpha-amylase and trypsin). Emphasis is laid on the enrichment of the mucus layer with pancreatic enzymes as compared with small intestinal juice. A hypothesis has been advanced according to which the mucus layer undergoes degradation of polymeric and oligomeric substrates, which plays a physiological part in the digestion of nutritive substances and protection of the internal medium against immunoactive biopolymers. The digestion occurring in the mucus layer is proposed to be called mucus digestion.

摘要

通过对酶活性进行组织化学和生化检测的方法已证实,覆盖小肠壁的黏液层含有活性酶(碱性磷酸酶、亮氨酸氨肽酶IV、蔗糖酶、乳糖酶)和胰腺酶(α-淀粉酶和胰蛋白酶)。与小肠液相比,黏液层富含胰腺酶这一点得到了强调。有人提出了一种假说,即黏液层会使聚合物和寡聚底物发生降解,这在营养物质的消化以及保护内环境免受免疫活性生物聚合物影响方面发挥着生理作用。发生在黏液层的消化过程被提议称为黏液消化。

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