Non-isothermal potential of phospholipid bilayer films.

The thermal electrical potential generated in isochemical conditions by a temperature gradient at the two sides of lipid bilayer leaflets is measured. The experimental results agree rather well with the theoretical predictions. The cephaline (from sheep brain) bilayer behaves like a film with zero charge while the phosphatidylcholine (from egg yolk) film performs like a charged membrane. The results presented suggest that the measurement of electrical thermal potential is an interesting method to investigate the electrical behaviour of bilayer membranes.