Greenfield J, Rea J, Ilfeld F W
Clin Orthop Relat Res. 1984 May(185):142-4.
A retrospective study of 67 patients in whom Morton's neuroma had been diagnosed showed that 78% were women. The average age was 58 years (range, 19-85 years). Pain in the forefoot, which worsened with walking, was relieved by removal of shoes. The presence of local interdigital tenderness led to the diagnosis. Modification of shoes was helpful in two patients. The other 65 patients received a series of interdigital Xylocaine-steroid injections at one- to three-week intervals, which immediately relieved the pain in 30% of the patients and gave partial relief in 50%. At a two-year follow-up examination, 80% of the patients indicated complete relief of pain or had only slight pain. Surgical excision was indicated in those who failed to respond to the injections. Of 11 patients, surgical excision successfully relieved pain in four, effected partial relief in four, and failed in three. As a result of this retrospective study of patients with Morton's neuroma, the authors recommend therapeutic injections prior to surgery.
一项对67例已确诊为莫顿神经瘤患者的回顾性研究表明，78%为女性。平均年龄为58岁（范围19 - 85岁）。前足疼痛，行走时加重，脱鞋后缓解。局部趾间压痛导致了诊断。两名患者通过修改鞋子得到缓解。其他65例患者每隔1至3周接受一系列趾间利多卡因 - 类固醇注射，30%的患者疼痛立即缓解，50%的患者部分缓解。在两年的随访检查中，80%的患者表示疼痛完全缓解或仅有轻微疼痛。对注射无反应者则进行手术切除。11例患者中，手术切除使4例患者疼痛成功缓解，4例部分缓解，3例失败。基于这项对莫顿神经瘤患者的回顾性研究，作者建议在手术前先进行治疗性注射。
