Ved Brat S, Williams G M
Food Chem Toxicol. 1984 Mar;22(3):211-5. doi: 10.1016/0278-6915(84)90129-7.
The effect of nitrilotriacetic acid on sister-chromatid exchanges (SCEs) in human peripheral blood lymphocytes and Chinese hamster ovary cells was studied. The chemical did not increase the frequency of SCEs in either cell type. The negative response of these cells supports other evidence that nitrilotriacetic acid is not genotoxic and that its carcinogenicity to the urinary tract may involve an epigenetic mechanism.
研究了次氮基三乙酸对人外周血淋巴细胞和中国仓鼠卵巢细胞姐妹染色单体交换（SCEs）的影响。该化学物质在两种细胞类型中均未增加SCEs的频率。这些细胞的阴性反应支持了其他证据，即次氮基三乙酸不具有遗传毒性，其对泌尿道的致癌性可能涉及一种表观遗传机制。
