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双腔/双心室起搏器治疗室性心动过速

DDD/DDT pacemakers in the treatment of ventricular tachycardia.

作者信息

Fisher J D, Furman S, Kim S G, Matos J A, Waspe L E

出版信息

Pacing Clin Electrophysiol. 1984 Mar;7(2):173-8. doi: 10.1111/j.1540-8159.1984.tb04883.x.

Abstract

The possibility of adapting multimode dual-chamber pacemakers for programmed and burst stimulation was explored in a group of patients with ventricular tachycardia. The potential usefulness and pitfalls of these pacemakers were exemplified in one patient, presented in detail. The implanted DDD pacemaker was programmed to an all-synchronous mode (DDT), permitting programmed ventricular stimulation through synchronization with chest wall stimulation provided by a standard external programmable stimulator. With the ventricular sensing refractory period shortened to 200 ms, both programmed electrical stimulation and burst pacing for termination of induced tachycardias were possible. When medications failed to offer protection against the patient's tachycardias, the ventricular sensing refractory period (and minimum stimulation interval) was increased to 300 ms, thereby permitting burst pacing at up to 200 beats/minute for termination of spontaneous episodes. After many trials to confirm the efficacy of such stimulation, and the lack of muscle potential triggering, the patient was discharged home with the pacemaker in the DDT mode. He was instructed to go to his local emergency room, and was equipped with a portable device to trigger his implanted unit. Subsequently, the patient had successful termination of several spontaneous episodes of ventricular tachycardia in an emergency room. Later, he began to experience palpitations during certain exercises, and it was found that the implanted unit was being triggered by pectoral myopotentials. The unit was therefore reprogrammed to decrease the sensitivity, and the patient was again discharged. The need for careful evaluation and close follow-up is emphasized to maximize the benefits and to minimize the very serious potential risks of this pacing mode.

摘要

在一组室性心动过速患者中探索了使多模式双腔起搏器适用于程控刺激和猝发刺激的可能性。这些起搏器的潜在用途和缺陷在一名患者中得到例证,并进行了详细介绍。植入的DDD起搏器被程控为全同步模式(DDT),通过与标准外部程控刺激器提供的胸壁刺激同步,允许进行程控心室刺激。将心室感知不应期缩短至200毫秒后,既可以进行程控电刺激,也可以进行猝发起搏以终止诱发的心动过速。当药物无法预防患者的心动过速时,将心室感知不应期(以及最小刺激间期)增加到300毫秒,从而允许以高达200次/分钟的频率进行猝发起搏以终止自发发作。在多次试验证实这种刺激的有效性以及不存在肌肉电位触发后,患者以DDT模式携带起搏器出院。患者被指示前往当地急诊室,并配备了一个便携式装置来触发其植入装置。随后,该患者在急诊室成功终止了几次自发性室性心动过速发作。后来,他在某些运动过程中开始出现心悸,发现植入装置被胸肌肌电位触发。因此对该装置进行了重新程控以降低灵敏度,患者再次出院。强调需要进行仔细评估和密切随访,以最大限度地提高这种起搏模式的益处,并将其非常严重的潜在风险降至最低。

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