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在无单胺氧化酶样活性的阿氏扁角水虻幼虫中存在5-羟基吲哚乙酸。

Presence of 5-hydroxy-indolacetic acid in Diloboderus abderus larvae without monoamine-oxidase-like activity.

作者信息

Rubio M C, Bonelli C G, Mastronardi I O, Rondina D C, Izquierdo J A

出版信息

Acta Physiol Lat Am. 1983;33(3):253-6.

PMID:6201039
Abstract

The authors confirmed the presence of monoamines and 5-hydroxy-indolacetic acid (5-HIAA) in the cephalic region of Diloboderus abderus larvae employing a high pressure liquid chromatography (HPLC) with electrochemical detector. An anticholinesterase insecticide produced an increase in the serotonin and 5-HIAA endogenous levels, and did not modify the catecholamines. Monoamine-oxidase activity was undetectable with a radioactive method using 3H-tyramine as substrate.

摘要

作者采用带电化学检测器的高压液相色谱法(HPLC),证实了阿氏锯角叶甲幼虫头部区域存在单胺类物质和5-羟吲哚乙酸(5-HIAA)。一种抗胆碱酯酶杀虫剂使血清素和5-HIAA内源性水平升高,且未改变儿茶酚胺类物质。用放射性方法以3H-酪胺为底物未检测到单胺氧化酶活性。

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