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通过不进行幽门成形术的胃肠吻合口闭合术治疗迷走神经切断术和胃肠吻合术后的严重副作用。

Treatment of severe side effects after vagotomy and gastroenterostomy by closure of gastroenterostomy without pyloroplasty.

作者信息

McMahon M J, Johnston D, Hill G L, Goligher J C

出版信息

Br Med J. 1978 Jan 7;1(6104):7-8. doi: 10.1136/bmj.1.6104.7.

Abstract

We describe nine patients who had severe, persistent abdominal pain, vomiting, dumping, or diarrhoea several years after truncal vagotomy and gastroenterostomy had been performed for duodenal ulceration. Each patient was judged to have a bad clinical result (Visick grade 4). There was no evidence of recurrent ulceration in any of the patients, and in each the patency of the pyloric canal was confirmed radiologically or endoscopically. Each patient was treated by simply dismantling the gastroenterostomy without addition for a pyloroplasty. In one patient the surgeon suspected that a vagal trunk might have been left intact, and a revagotomy was performed by the "highly selective" technique. Postoperatively, none of the patients developed gastric retention. Symptomatic improvement occurred in eight patients, and four of them achieved perfect results (Visick grade 1). Side effects are common after vagotomy and gastroenterostomy, and are largely attributable to the presence of the gastroenterostomy stoma. Our results show that the symptoms may be alleviated by closing the gastroenterostomy, without precipitating gastric retention.

摘要

我们描述了9例患者,他们在因十二指肠溃疡接受迷走神经干切断术和胃肠吻合术后数年出现严重、持续性腹痛、呕吐、倾倒综合征或腹泻。每例患者的临床结果均较差(Visick 4级)。所有患者均无复发性溃疡的证据,且经放射学或内镜检查证实每例患者的幽门管通畅。每例患者均仅通过拆除胃肠吻合术进行治疗,未加做幽门成形术。1例患者,外科医生怀疑有一条迷走神经干可能未被切断,遂采用“高选择性”技术再次行迷走神经切断术。术后,所有患者均未发生胃潴留。8例患者症状改善,其中4例效果理想(Visick 1级)。迷走神经切断术和胃肠吻合术后副作用常见,主要归因于胃肠吻合口的存在。我们的结果表明,关闭胃肠吻合口可缓解症状,且不会引发胃潴留。

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