Shashkova N G, Avanesova T S
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(11):1670-6.
The authors studied 53 patients with hysterical neurosis and 66 with hysterical neurotic development of personality. Factors contributing to an unfavourable course of neurosis and its transformation into a hysterical development were elicited; clinical variants of the formation of the hysterical neurotic personality development are described. A study was carried out aimed at comparing the functions of the serotoninergic and cholinergic systems in patients with hysterical neurosis, hysterical development and hysteroid psychopathy at the stage of decompensation. An increase in the changes in these systems in the "neurosis-development-psychopathy" series and their time-course were defined in the process of treatment. On the basis of the clinical and laboratory data, a conclusion was drawn about the advantage of treating the hysterical development with phenothiazine drugs as compared with tranquilizers.
作者研究了53例癔症性神经症患者和66例具有癔症性人格发展的患者。找出了导致神经症病程不利及其转变为癔症性发展的因素;描述了癔症性神经症人格发展形成的临床变体。进行了一项研究,旨在比较处于失代偿期的癔症性神经症、癔症性发展和类癔症精神病患者中5-羟色胺能和胆碱能系统的功能。在治疗过程中确定了这些系统在“神经症-发展-精神病”系列中的变化增加及其时间进程。根据临床和实验室数据,得出结论:与镇静剂相比,用吩噻嗪类药物治疗癔症性发展更具优势。