Gardner J D, Jensen R T
Am J Physiol. 1984 May;246(5 Pt 1):G471-6. doi: 10.1152/ajpgi.1984.246.5.G471.
Since 1979 three classes of cholecystokinin receptor antagonists have been described: 1) derivatives of cyclic nucleotides, 2) derivatives of amino acids, and 3) C-terminal fragments or partial sequences of cholecystokinin. These various antagonists share a number of common features, such as their specific, reversible, and competitive actions, but they vary in the potency with which they inhibit the actions of cholecystokinin.
自1979年以来,已描述了三类胆囊收缩素受体拮抗剂:1)环核苷酸衍生物,2)氨基酸衍生物,3)胆囊收缩素的C末端片段或部分序列。这些不同的拮抗剂具有许多共同特征,例如它们的特异性、可逆性和竞争性作用,但它们抑制胆囊收缩素作用的效力各不相同。