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盐依赖性血凝麻疹病毒的一些特性。

Some characteristics of salt-dependent haemagglutinating measles viruses.

作者信息

Shirodaria P V, Dermott E, Gould E A

出版信息

J Gen Virol. 1976 Oct;33(1):107-15. doi: 10.1099/0022-1317-33-1-107.

Abstract

Several strains of measles virus which did not agglutinate monkey erythrocytes in phosphate-buffered saline did so in buffer containing 0-8 M-ammonium sulphate. Haemadsorption to cells infected with these viruses was also salt-dependent. In a series of tests salt-dependent agglutinin was shown to be a stable structural component of the infectious virion. The relevance of these findings is discussed in the light of previous reports that many measles virus preparations do not agglutinate erythrocytes.

摘要

几种在磷酸盐缓冲盐水中不能凝集猴红细胞的麻疹病毒株,在含有0.8M硫酸铵的缓冲液中却能凝集。这些病毒感染的细胞的血细胞吸附作用也依赖于盐。在一系列试验中,盐依赖性凝集素被证明是感染性病毒粒子的一种稳定结构成分。根据之前许多麻疹病毒制剂不能凝集红细胞的报道,对这些发现的相关性进行了讨论。

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