Keel B A, Abney T O
Experientia. 1984 May 15;40(5):503-5. doi: 10.1007/BF01952408.
Fluid obtained from rat fetuses was utilized to characterize the affinity, number of binding sites, and the association and dissociation rate kinetics of the binding of estradiol and estrone to AFP. Statistical analysis demonstrated no differences when the values for the AFP-estradiol interaction were compared with those obtained for the ATP-estrone interaction. These data demonstrate that rat AFP specifically binds estradiol and estrone with a high capacity, high affinity, and similar binding kinetics.
从大鼠胎儿获取的液体被用于表征雌二醇和雌酮与甲胎蛋白（AFP）结合的亲和力、结合位点数量以及结合和解离速率动力学。统计分析表明，将AFP - 雌二醇相互作用的值与AFP - 雌酮相互作用的值进行比较时，没有差异。这些数据表明，大鼠AFP以高容量、高亲和力和相似的结合动力学特异性结合雌二醇和雌酮。
