大鼠肝脏胞质溶胶中存在二氢二醇脱氢酶和3α-羟基类固醇脱氢酶，但兔肝脏胞质溶胶中不存在。
Identity of dihydrodiol dehydrogenase and 3 alpha-hydroxysteroid dehydrogenase in rat but not in rabbit liver cytosol.
作者信息
Wörner W, Oesch F
出版信息
FEBS Lett. 1984 May 21;170(2):263-7. doi: 10.1016/0014-5793(84)81325-3.
PMID:6202552
Abstract
Dihydrodiol dehydrogenase and 3 alpha-hydroxysteroid dehydrogenase activity in rat and rabbit liver cytosol have been analyzed by isoelectric focussing and subsequent activity staining. Identity of the two enzymes in rat liver cytosol is demonstrated. At least 4 main enzyme forms possessing dihydrodiol dehydrogenase activity can be detected in rabbit liver cytosol. However, in this species, only one of these forms has measurable activity towards 3 alpha-hydroxysteroids.
摘要
已通过等电聚焦及后续活性染色分析了大鼠和兔肝脏胞质溶胶中的二氢二醇脱氢酶和3α-羟基类固醇脱氢酶活性。证实了大鼠肝脏胞质溶胶中这两种酶的一致性。在兔肝脏胞质溶胶中可检测到至少4种具有二氢二醇脱氢酶活性的主要酶形式。然而，在该物种中，这些形式中只有一种对3α-羟基类固醇具有可测量的活性。
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