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小龙虾神经末梢中的突触强度与辣根过氧化物酶摄取

Synaptic strength and horseradish peroxidase uptake in crayfish nerve terminals.

作者信息

Thompson C S, Atwood H L

出版信息

J Neurocytol. 1984 Apr;13(2):267-80. doi: 10.1007/BF01148119.

DOI:10.1007/BF01148119
PMID:6202849
Abstract

Uptake of horseradish peroxidase was studied by examining percentages of labelled synaptic vesicles in nerve endings of the excitatory axon innervating the opener muscle of the walking leg in the crayfish (Procambarus clarkii). Terminals on fibres with large excitatory postsynaptic potentials (EPSP) had higher percentage of labelled vesicles than terminals of fibres with small EJPs. The extent of labelling in the synaptic vesicle pool was greater for terminals with higher transmitter output. Evidence for three possible routes of synaptic vesicle formation was found. Movement of vesicles within the terminal as a whole appeared to be constrained, but rapid movement of vesicles within local populations probably occurs.

摘要

通过检测辣根过氧化物酶在小龙虾(克氏原螯虾)步行腿开肌兴奋性轴突神经末梢中标记突触小泡的百分比,研究了其摄取情况。具有大兴奋性突触后电位(EPSP)的纤维上的终末,其标记小泡的百分比高于具有小兴奋性突触后电位(EJP)的纤维的终末。递质输出较高的终末,其突触小泡池中的标记程度更大。发现了突触小泡形成的三种可能途径的证据。突触小泡在整个终末内的移动似乎受到限制,但局部群体内的突触小泡可能会快速移动。

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