硫酸乙酰肝素结构与血管生成的调节
Heparan structure and the modulation of angiogenesis.
作者信息
Long W F, Williamson F B
出版信息
Med Hypotheses. 1984 Apr;13(4):385-94. doi: 10.1016/0306-9877(84)90071-9.
PMID:6203020
Abstract
It is postulated that the angiogenic potential of tissues is influenced by the fine structure of heparan glycosaminoglycans present in the tissues. Possible mechanisms involved are discussed. It is suggested that compounds chemically related to heparans might usefully act as inhibitors of pathological angiogenesis.
摘要
据推测，组织的血管生成潜力受组织中存在的硫酸乙酰肝素糖胺聚糖精细结构的影响。文中讨论了可能涉及的机制。有人提出，与硫酸乙酰肝素化学相关的化合物可能有效地充当病理性血管生成的抑制剂。
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