Bloch B, Nel C P, Kriel A, Atad J, Goldberg G
Cancer Treat Rep. 1984 Jun;68(6):891-3.
Seventeen patients with advanced and recurrent squamous cell cervical cancer were treated with a combination of cisplatin and bleomycin. One complete and nine partial responses were observed (53%). The median duration of response was 8 months and the median survival was 12.7 months (5 months for nonresponders). Response was documented, particularly in patients with nodal disease and lung metastases. No life-threatening toxic effects were reported. This combination appears to be as effective as other combinations, has low toxicity, is well-tolerated, and merits further study.
17例晚期复发性宫颈鳞状细胞癌患者接受了顺铂和博来霉素联合治疗。观察到1例完全缓解和9例部分缓解（53%）。缓解的中位持续时间为8个月，中位生存期为12.7个月（无反应者为5个月）。有反应得到记录，特别是在有淋巴结疾病和肺转移的患者中。未报告危及生命的毒性作用。这种联合治疗似乎与其他联合治疗一样有效，毒性低，耐受性好，值得进一步研究。
