• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Possible involvement of folate cycle in the pathogenesis of amyotrophic lateral sclerosis.

作者信息

Yoshino Y

出版信息

Neurochem Res. 1984 Mar;9(3):387-91. doi: 10.1007/BF00963985.

DOI:10.1007/BF00963985
PMID:6204220
Abstract

The folate cycle, which has a close correlation with nucleic acid synthesis as well as with sulfur amino acid metabolism, may have some bearing on the pathogenesis of amyotrophic lateral sclerosis. The folate cycle hypothesis offers a unified explanation of the reduction of RNA and the elevation of taurine in nervous tissue of this disease.

摘要

相似文献

1
Possible involvement of folate cycle in the pathogenesis of amyotrophic lateral sclerosis.
Neurochem Res. 1984 Mar;9(3):387-91. doi: 10.1007/BF00963985.
2
[Folate derivatives in motor cortex of amyotrophic lateral sclerosis (author's transl)].
Rinsho Shinkeigaku. 1981 Feb;21(2):93-6.
3
Free amino acids in motor cortex of amyotrophic lateral sclerosis.
Experientia. 1979 Feb 15;35(2):219-20. doi: 10.1007/BF01920627.
4
[Free amino acids and activities of folate-derivative converting enzymes in nervous system of rats administered with beta, beta'-iminodipropionitrile].[给予β,β'-亚氨基二丙腈的大鼠神经系统中游离氨基酸及叶酸衍生物转化酶的活性]
Rinsho Shinkeigaku. 1993 Aug;33(8):862-9.
5
A new hypothesis of the etiology of amyotrophic lateral sclerosis. The DNA hypothesis.肌萎缩侧索硬化症病因的新假说。DNA假说。
Arch Neurol. 1982 Nov;39(11):677-80. doi: 10.1001/archneur.1982.00510230003001.
6
DNA hypothesis of amyotrophic lateral sclerosis.肌萎缩侧索硬化症的DNA假说
Adv Neurol. 1982;36:493-502.
7
The ratio of N-acetyl aspartate to glutamate correlates with disease duration of amyotrophic lateral sclerosis.N-乙酰天门冬氨酸与谷氨酸的比值与肌萎缩侧索硬化症的病程相关。
J Clin Neurosci. 2016 May;27:110-3. doi: 10.1016/j.jocn.2015.08.044. Epub 2016 Jan 4.
8
[Changes in cysteine sulfinic acid in rat brain under the experimental elevation of taurine content].[实验性提高牛磺酸含量时大鼠脑内半胱亚磺酸的变化]
Rinsho Shinkeigaku. 1996 May;36(5):648-54.
9
Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis.来自肌萎缩侧索硬化症症状前小鼠模型的皮质运动神经元的功能、形态及囊泡谷氨酸转运体表达的改变
Cereb Cortex. 2016 Apr;26(4):1512-28. doi: 10.1093/cercor/bhu317. Epub 2015 Jan 16.
10
[MR imaging of amyotrophic lateral sclerosis].[肌萎缩侧索硬化症的磁共振成像]
Nihon Igaku Hoshasen Gakkai Zasshi. 1992 Apr 25;52(4):427-35.

本文引用的文献

1
Aminoaciduria in pernicious anaemia and subacute combined degeneration of the cord.恶性贫血及脊髓亚急性联合变性中的氨基酸尿症
Lancet. 1954 Jun 12;266(6824):1212-3. doi: 10.1016/s0140-6736(54)92445-9.
2
[Folate derivatives in motor cortex of amyotrophic lateral sclerosis (author's transl)].
Rinsho Shinkeigaku. 1981 Feb;21(2):93-6.
3
[Activities of folate-derivative converting enzymes in the brain of patients with amyotrophic lateral sclerosis].
Rinsho Shinkeigaku. 1983 Jul;23(7):563-9.
4
A new hypothesis of the etiology of amyotrophic lateral sclerosis. The DNA hypothesis.肌萎缩侧索硬化症病因的新假说。DNA假说。
Arch Neurol. 1982 Nov;39(11):677-80. doi: 10.1001/archneur.1982.00510230003001.
5
RNA content and volume of motor neurons in amyotrophic lateral sclerosis. I. The cervical swelling.肌萎缩侧索硬化症中运动神经元的RNA含量和体积。I. 颈膨大
J Neuropathol Exp Neurol. 1981 Jan;40(1):32-6.
6
RNA content and volume of motor neurons in amyotrophic lateral sclerosis. II. The lumbar intumescence and nucleus dorsalis.
J Neuropathol Exp Neurol. 1981 Mar;40(2):187-92. doi: 10.1097/00005072-198103000-00009.
7
Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions.
Can J Biochem. 1970 Mar;48(3):228-35. doi: 10.1139/o70-042.
8
The effect of folate deficiency on neuronal RNA content. A quantitative cytochemical study.叶酸缺乏对神经元RNA含量的影响。一项定量细胞化学研究。
Br J Exp Pathol. 1970 Apr;51(2):191-6.
9
[Free amino acids in the spinal cord of a patient with amyotrophic lateral sclerosis].[肌萎缩侧索硬化症患者脊髓中的游离氨基酸]
Rinsho Shinkeigaku. 1976 Sep;16(11-3ENA-NA-770111-770112):768-74.
10
RNA synthesis in normal and Newcastle disease virus infected mice.正常小鼠和感染新城疫病毒的小鼠中的RNA合成
J Neurochem. 1979 Feb;32(2):633-5. doi: 10.1111/j.1471-4159.1979.tb00396.x.