Hanson J S
Pacing Clin Electrophysiol. 1984 May;7(3 Pt 1):389-94. doi: 10.1111/j.1540-8159.1984.tb04923.x.
During a 44-month period, 105 Medtronic model 6972-58 polyurethane-insulated, bipolar ventricular pacing leads were implanted, of which 16 failed clinically at a mean of 20.5 months post-implant. Pacing dysfunction presented as either intermittent or complete loss of sensing and/or capture and, rarely, oversensing . Thirteen of the 16 patients were asymptomatic, and problems were detected in 11 instances during routine telephonic surveillance. At the time of lead replacement, low or widely fluctuating lead resistance values and high current drain were uniformly observed. The single lead capable of total extraction revealed rupture of both internal and external insulation. A brief summary of the currently much-discussed "polyurethane controversy" is presented, and the issue of patient management is discussed.
在44个月的时间里，植入了105根美敦力6972 - 58型聚氨酯绝缘双极心室起搏导线，其中16根在植入后平均20.5个月出现临床故障。起搏功能障碍表现为间歇性或完全丧失感知和/或夺获，很少出现感知过度。16例患者中有13例无症状，11例在常规电话监测中发现问题。在更换导线时，均观察到导线电阻值低或波动较大以及电流消耗高的情况。唯一一根能够完全取出的导线显示内部和外部绝缘均破裂。本文简要总结了当前备受讨论的“聚氨酯争议”，并讨论了患者管理问题。
