Flamm J
Wien Med Wochenschr. 1984 Apr 15;134(7):147-51.
This is a report on the therapeutical results in 38 patients with advanced renal cell carcinoma (Robson stage III and IV). We compared: palliative tumour nephrectomy (n = 10), transfemoral embolisation of the tumour or operative occlusion of the renal vessels (n = 6) and tumours which were primarily or secondarily inoperative (n = 22). In Robson stage II 3 out of 8 patients died after palliative nephrectomy and 6 out of 8 patients died after laparotomy. In Robson stage IV 1 out of 2 patients died after palliative nephrectomy, 5 out of 6 patients died after embolisation and 12 out of 14 patients died before or after laparotomy. The 3 year survival rate for patients with a tumour Robson stage III was 3 out of 8 after palliative nephrectomy whereas none of the patients survived after laparotomy, or without operative treatment. In Robson stage IV none of the patients survived after nephrectomy, only 1 survived after embolisation and 1 patient survived without operative treatment for 3 years. The result of this retrospective study shows that tumour nephrectomy is advisable in Robson stage III with only focalised metastasis of the lymph nodes (N1-2), whereas there are no favourable results in Robson stage IV with an advanced metastasis of the lymph nodes.
这是一份关于38例晚期肾细胞癌(罗布森分期III期和IV期)治疗结果的报告。我们比较了:姑息性肿瘤肾切除术(n = 10)、经股动脉肿瘤栓塞术或肾血管手术闭塞术(n = 6)以及原发性或继发性无法手术的肿瘤(n = 22)。在罗布森II期,8例患者中有3例在姑息性肾切除术后死亡,8例患者中有6例在剖腹术后死亡。在罗布森IV期,2例患者中有1例在姑息性肾切除术后死亡,6例患者中有5例在栓塞术后死亡,14例患者中有12例在剖腹术前或术后死亡。罗布森III期肿瘤患者姑息性肾切除术后3年生存率为8例中的3例,而剖腹术后或未经手术治疗的患者无一存活。在罗布森IV期,肾切除术后患者无一存活,栓塞术后仅1例存活,1例患者未经手术治疗存活3年。这项回顾性研究的结果表明,对于罗布森III期仅伴有局限性淋巴结转移(N1 - 2)的患者,肿瘤肾切除术是可取的,而对于伴有晚期淋巴结转移的罗布森IV期患者,没有良好的治疗效果。