Hansson C
Acta Derm Venereol. 1984;64(3):185-90.
The presence of 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI-2-C) in normal human urine was demonstrated by mass spectrometry. A quantitative method based on HPLC with fluorometric detection was developed for the determination of 6H5MI-2-C. In normal subjects the mean urinary concentration of 6H5MI-2-C was 38 mumol/mol of creatinine (range 6-76 mumol/mol).
通过质谱法证实了正常人尿液中存在6-羟基-5-甲氧基吲哚-2-羧酸(6H5MI-2-C)。开发了一种基于高效液相色谱荧光检测的定量方法来测定6H5MI-2-C。在正常受试者中,6H5MI-2-C的尿平均浓度为38μmol/mol肌酐(范围为6-76μmol/mol)。